KMID : 0363220140520080563
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Korean Journal of Dermatology 2014 Volume.52 No. 8 p.563 ~ p.566
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Bullous Scabies with Bullous Pemphigoid
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Kang Jin-Hee
Lee Ji-Hyun Kim Tae-Yoon
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Abstract
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We report a rare case of bullous scabies with bullous pemphigoid in a 59-year-old male patient. He presented with a 9-month history of exhibiting multiple, variable-sized, red-to-brown, pruritic cutaneous patches, and papules with tense bullae on his whole body. A direct smear of the bullous lesions was performed and was negative for scabies mites. Histopathologic findings (hematoxylin and eosin staining) revealed Sarcoptes scabiei in the stratum corneum. There were sub-epidermal blisters with massive eosinophil and lymphocyte infiltration in the epidermis and upper dermis. Direct immunofluorescence microscopy showed linear deposition of IgG at the dermo-epidermal junction. Indirect immunofluorescence microscopy of samples acquired for the salt-split skin test showed linear IgG deposition in the epidermis. Skin lesions improved after the patient was treated with an anti-scabietic and steroids.
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KEYWORD
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Bullous pemphigoid, Bullous scabies
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